Ulysses L. Houston (1825-1889) was a pastor and state legislator in Georgia. Considered a leading citizen of the Black community in Savannah, he was elected to the Georgia State Legislature as a representative of Bryan County. Born into slavery in Grahamville, South Carolina, he moved with his enslaver, Moses Henderson, to serve in the Henderson home. Licensed to preach in 1855, he was the first member of the Third African Baptist Church, which is now the First Bryan Baptist Church in Savannah, Georgia. He then served as a pastor from 1861 until his passing in 1889. He was one of the church leaders who met with General Sherman in Savannah to discuss the future of the Black community in Savannah. In addition to his church leadership, he was a founding member of the fraternal lodge, Eureka Lodge, No. 1, A. F. and A. M. He also founded Houston Baptist Church in Port Wentworth.

Houston was married to Henrietta. They had four sons and one daughter. He was a respected man around the South. When he passed, over 7000 people attended his funeral. He is buried in Laurel Grove South Cemetery.